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Moving to 3D: Quantifying Virtual Surgical Planning Accuracy Using Geometric Morphometrics and Cephalometrics in
Sophia Hu1, Julie Lawrence2, Calvin R Schuster3
1Division of Plastic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston.
The Journal of Craniofacial Surgery
|April 18, 2025
Summary
Facial feminization surgery (FFS) outcomes for genioplasty and mandibular contouring were accurately predicted using virtual surgical planning (VSP). Postoperative results closely matched planned shapes, validating VSP
Area of Science:
- Plastic Surgery
- 3D Imaging
- Quantitative Analysis
Background:
- Facial feminization surgery (FFS) aims to feminize facial features in transgender women.
- Virtual surgical planning (VSP) is used to improve predictability in FFS.
- Quantifying shape changes in FFS is challenging due to multi-dimensional alterations.
Purpose of the Study:
- To apply cephalometric and geometric morphometric analyses to evaluate shape changes in FFS patients.
- To assess the accuracy of virtual surgical planning (VSP) in genioplasty and mandibular contouring.
Main Methods:
- 3D reconstructions from preoperative, postoperative, and VSP-guided scans of 14 FFS patients.
- Analysis using cephalometrics and geometric morphometrics (Generalized Procrustes Analysis).
- Comparison of postoperative scans with VSP-predicted shapes.
Main Results:
- Postoperative bigonial width significantly aligned with planned values.
- Geometric morphometrics confirmed significant alignment between postoperative and planned scans for specific procedures.
- Deviations from planned shapes were often intermediate between preoperative and planned states, possibly due to surgical modifications.
Conclusions:
- Virtual surgical planning (VSP) demonstrates high accuracy in predicting bony shape changes for genioplasty and mandibular contouring in FFS.
- Cephalometrics and geometric morphometrics are effective tools for quantifying FFS outcomes.
- Further research with more landmarks may enhance the evaluation of bony changes in FFS.

