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Early-Life Quarantine Increases the Development of Infant Atopic Dermatitis: A Birth Cohort Study in China

Yi Hu1,2,3, Jiuru Zhao1,2,3, Qianwen Shen1,2,3

  • 1The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Allergy
|April 19, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
atopic Dermatitisenvironment and hygiene hypothesisepidemiology

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Development of Immunocompetence01:22

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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
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