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Updated: May 10, 2025

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Published on: March 12, 2018
Pathological insights into small cell osteosarcoma: A rare case report highlighting diagnostic approaches with a
Bhaskar Narayan1, Kuldeep Singh1, Jeyaseelan Augustine1
1Department of Oral & Maxillofacial Pathology and Microbiology, Maulana Azad Institute of Dental Sciences, BSZ Marg, New Delhi 110002, India.
Abstract:
Small cell osteosarcoma (SCOS) is an uncommon variant of osteosarcoma, typically affecting young adults. This case report presents an unusual case of a 35-year-old individual who presented with a growth in the mandible. Microscopically, the lesion was characterised by sheets and plexuses of atypical small round cells with minimal osteoid formation. PAS positivity in the tumour osteoid and SATB2 immunopositive tumour cells led to diagnosis of SCOS.

