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Updated: Jun 14, 2025

Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing
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Unveiling the BRAF fusion structure variations through DNA and RNA sequencing

Qiong Yang1,2, Baoming Wang3, Xuli Meng4

  • 1Center for Plastic & Reconstructive Surgery, Department of Lymphatic surgery and reconstructive microsurgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.

British Journal of Cancer
|April 19, 2025
PubMed
Summary

Next-generation sequencing (NGS) is crucial for detecting BRAF fusions in various cancers, predominantly glioma. Comprehensive molecular profiling and RNA sequencing improve accuracy for targeted BRAF fusion therapies.

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