Response to: Evaluating time-lapse imaging systems for embryo incubation and selection in ART: a critical review of a...

The concerns raised by the authors of this commentary are largely addressed in the paper and the requested information is available in the supplementary materials and the published trial protocol referenced in the paper. We have further detailed some information to address their concerns. The planned effect size was based on the results reported by the largest randomized controlled trial at the start of our trial and supported by peer review and patient and clinician input. The trial was powered for the primary outcome of live birth, which we have reported. All reported secondary outcomes and subgroup analyses are only hypothesis generating.