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Bisphosphonate and medication induced necrosis of jaws
1Department of oral and Maxillofacial Surgery Government Dental College Srinagar-190010, Jammu and Kashmir, India.
Abstract:
The bisphosphonates are prescribed drugs to prevent bone resorption particularly in patients having certain malignancies. However, there is a potential risk of osteonecrosis of jaws in patients receiving dental treatment. Therefore, it is of interest to evaluate the chances of osteonecrosis in patients referred for management of osteonecrosis in whom dental treatment was carried out by the referring dental professionals. Hence, 86 patients were studied, where 18 patients had developed osteonecrosis particularly after dental extraction of which 13 patients were having underlying malignancy. We found that medication induced necrosis of jaws is more in patients with underlying malignancy or other co-morbidities. Moreover, extraction is a trigger in such patients for developing the debilitating condition.
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