Jove
Visualize
Contact Us

Related Concept Videos

Overview of Biostatistics in Health Sciences01:19

Overview of Biostatistics in Health Sciences

285
Biostatistics involves the application of statistical techniques to scientific research in health-related fields, including biology and public health. These techniques are essential for designing studies, collecting data, and analyzing it to draw meaningful conclusions. Given the complexity of biological processes, particularly in studies involving human subjects, biostatistical methods are crucial for effectively organizing and interpreting data that might otherwise obscure underlying patterns...
285
Biostatistics: Overview01:20

Biostatistics: Overview

203
Biostatistics plays a crucial role in understanding and analyzing data in healthcare and biology. Biostatisticians conduct experiments, gather evidence, and draw meaningful conclusions using statistical methods and techniques. Different variables form the foundation of biostatistical analysis, allowing researchers to understand and interpret data effectively. These variables are classified into different types, each serving a specific purpose in statistical analysis.
Discrete variables are...
203
Hazard Ratio01:12

Hazard Ratio

67
The hazard ratio (HR) is a widely used measure in clinical trials to compare the risk of events, such as death or disease recurrence, between two groups over time. It reflects the ratio of hazard rates—the instantaneous risk of the event occurring—between a treatment group and a control group. This measure provides valuable insights into the relative effectiveness of a treatment by assessing how the risk of an event differs between the two groups.
For example, in a clinical trial...
67
Statistical Methods for Analyzing Epidemiological Data01:25

Statistical Methods for Analyzing Epidemiological Data

237
Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
237
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

106
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
106
Statistical Software for Data Analysis and Clinical Trials01:12

Statistical Software for Data Analysis and Clinical Trials

314
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
314

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Systemic Medications and Their Ocular Side Effects.

Cureus·2025
Same author

A meta-analysis of the association between high-sensitivity c-reactive protein level and glaucoma.

European journal of ophthalmology·2024
Same author

Common causes of visual impairment in the elderly.

Medical hypothesis, discovery & innovation ophthalmology journal·2023
Same author

Coronavirus disease pandemic and dry eye disease: A methodology concern on the causal relationship.

Medical hypothesis, discovery & innovation ophthalmology journal·2023
Same author

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19.

Journal of visualized experiments : JoVE·2022
Same author

Ocular manifestations of COVID-19.

Therapeutic advances in ophthalmology·2022
Same journal

Retraction: The Association Between Janus Kinase 2 and Factor V Leiden Mutations and Thrombotic Complications in Patients With Myeloproliferative Disorders: A Study From Saudi Arabia.

Cureus·2026
Same journal

Patient-Reported Understanding of Emergency Department Discharge Instructions, Satisfaction, and Acceptability of a Future Telemedicine-Based Call-Back Program: Phase 1 Observational Pilot Study at a Tertiary Hospital in Dubai, United Arab Emirates.

Cureus·2026
Same journal

Correction: Methylprednisolone-Induced Delayed and Sustained Bradycardia in Multisystem Inflammatory Syndrome in Children.

Cureus·2026
Same journal

Rapid Interval Development of a Left Hepatic Artery Pseudoaneurysm During Acute Interstitial Edematous Pancreatitis.

Cureus·2026
Same journal

Recurrent Acute Pancreatitis Secondary to Untreated Hyperparathyroidism: A Case Report and Literature Review.

Cureus·2026
Same journal

A Prospective Case-Control Study of Helicobacter pylori and Systemic Inflammation in Colorectal Cancer Pathogenesis.

Cureus·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 10, 2025

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
08:36

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Published on: April 19, 2024

396

Meta-Analysis: A to Z for Healthcare Professionals.

Mashael Al-Namaeh1

  • 1Clinical Research, Clinical Virtual Research Center, Wayne, USA.

Cureus
|April 21, 2025
PubMed
Summary
This summary is machine-generated.

This guide demonstrates meta-analysis using JASP software for medical research. It found no link between vitamin D and primary open-angle glaucoma, but highlighted challenges in glaucoma and cardiovascular disease studies.

Keywords:
egger statistical testforest plotfunnel plotmeta-analysisrisk ratiostandard mean difference

More Related Videos

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
07:51

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Published on: September 26, 2018

7.5K
Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
04:34

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia

Published on: February 17, 2023

919

Related Experiment Videos

Last Updated: May 10, 2025

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
08:36

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Published on: April 19, 2024

396
Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
07:51

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Published on: September 26, 2018

7.5K
Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
04:34

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia

Published on: February 17, 2023

919

Area of Science:

  • Ophthalmology
  • Biostatistics
  • Evidence-Based Medicine

Background:

  • Meta-analysis is crucial for synthesizing medical research to improve clinical decisions.
  • Open-source statistical software like JASP offers accessible tools for complex analyses.
  • Glaucoma, a leading cause of blindness, necessitates robust research into its risk factors and comorbidities.

Purpose of the Study:

  • To provide a practical, step-by-step guide for conducting meta-analyses using JASP.
  • To illustrate JASP's application through case studies on glaucoma and related health conditions.
  • To assess the association between serum vitamin D and intraocular pressure in primary open-angle glaucoma (POAG).
  • To evaluate the relationship between cardiovascular mortality and open-angle glaucoma (OAG).

Main Methods:

  • The study followed PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines.
  • A random-effects model was employed to manage statistical heterogeneity across studies.
  • JASP (Jeffreys's Amazing Statistics Program) was used for all meta-analysis procedures.
  • Two distinct meta-analyses were performed: vitamin D and POAG, and cardiovascular mortality and OAG.

Main Results:

  • No statistically significant association was found between serum vitamin D levels and primary open-angle glaucoma (p = 0.122).
  • The meta-analysis examining cardiovascular disease and open-angle glaucoma exhibited substantial heterogeneity (I² = 99.54%).
  • The high heterogeneity indicates significant variability in the data, posing challenges for interpretation.

Conclusions:

  • JASP provides a valuable, user-friendly platform for conducting meta-analyses in medical research.
  • The findings underscore the importance of critically evaluating heterogeneity in meta-analyses, especially in complex conditions like glaucoma.
  • Further research is needed to clarify the relationship between cardiovascular health and glaucoma, considering the observed heterogeneity.