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Ocular biological characteristics and refractive errors in children with unilateral congenital ptosis

Yu-Ying Sun1, Bing-Ying Lin2, Zhen Mao2

  • 1Department of Ophthalmology, the Third Affiliated Hospital of GuangZhou University of Chinese Medicine, Guangzhou 510060, Guangdong Province, China.

International Journal of Ophthalmology
|April 21, 2025
PubMed

Insights

Children with unilateral congenital ptosis have longer axial lengths and flatter, thicker corneas. Congenital ptosis also elevates the risk of amblyopia, underscoring the need for regular eye exams.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Ocular Biometry

Background:

  • Unilateral congenital ptosis can affect visual development.
  • Understanding ocular characteristics in affected children is crucial for management.

Purpose of the Study:

  • To evaluate refractive status and ocular biological parameters in children with unilateral congenital ptosis.
  • To compare these parameters between ptotic and fellow eyes.

Main Methods:

  • Cross-sectional study of 200 Chinese children (3-15 years) with unilateral congenital ptosis.
  • Cycloplegic refraction and ocular biometry measurements were performed.
  • Data collected between October 2020 and August 2022.

Main Results:

  • Ptotic eyes exhibited significantly higher prevalence of with-the-rule and oblique astigmatism.
  • Corneas were flatter, thicker, and smaller (white-to-white) in ptotic eyes.
  • Ptotic eyes had longer axial length (AL) and a higher incidence of amblyopia (32.0%).

Conclusions:

  • Congenital ptosis is associated with specific ocular biometric changes, including longer AL and altered corneal morphology.
  • Ptotic eyes present a significantly increased risk for amblyopia.
  • Regular monitoring of refractive error and ocular parameters is essential for early intervention in children with unilateral congenital ptosis.
Abstract

Keywords:
axis lengthcongenital ptosisocular biological characteristics

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