Related Experiment Video
Updated: May 10, 2025
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Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis
Published on: October 2, 2020
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Recurrent Intradialytic Hypotension, Associated Risk Factors, and Outcomes in Northern Tanzania: A Retrospective
Fuad H Said1, Venance P Maro1,2, Abid M Sadiq1,2
1Department of Internal Medicine Kilimanjaro Christian Medical University College Moshi Tanzania.
Health Science Reports
|April 21, 2025
Summary
Recurrent intradialytic hypotension (IDH) during hemodialysis (HD) is linked to male gender and hyperphosphatemia. Lower systolic blood pressure (<140 mmHg) offers protection against IDH episodes in Sub-Saharan African patients.
Area of Science:
- Nephrology
- Internal Medicine
- Clinical Research
Background:
- Intradialytic hypotension (IDH) is a frequent complication of hemodialysis (HD), associated with adverse outcomes.
- Data regarding IDH incidence and risk factors in Sub-Saharan Africa is limited.
Purpose of the Study:
- To determine the incidence, risk factors, and outcomes of recurrent IDH in patients undergoing maintenance HD.
- To investigate the association between pre-dialytic serum inorganic phosphate levels and recurrent IDH.
Main Methods:
- Retrospective cohort study analyzing 4706 HD sessions at Kilimanjaro Christian Medical Centre.
- Inclusion criteria applied to 39 patients; recurrent IDH was the primary predictor.
- Statistical analyses included chi-squared tests and ROC curve analysis to identify risk factors.
Main Results:
- The incidence of IDH was 4.35%, with 46.3% of episodes being recurrent.
- Hyperphosphatemia (serum inorganic phosphate >1.8 mmol/L) and male gender were significant risk factors for recurrent IDH.
- Systolic blood pressure <140 mmHg demonstrated a protective effect against recurrent IDH.
Conclusions:
- Recurrent IDH is more prevalent in males and associated with hyperphosphatemia.
- Seasonal variations may influence IDH occurrence.
- Maintaining systolic blood pressure below 140 mmHg appears protective against recurrent IDH.
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