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A simplified treatment algorithm for chronic scrotal content pain syndrome
Sergey Kravchick1, Sijo J Parekattil2, Gennady Bratslavsky3
1Arthur Smith Institute for Urology of the Northwell Health System, Riverhead, NY, USA.
Current Urology
|April 21, 2025
Summary
Chronic scrotal content pain (CSCP) is a common urology issue. This study categorizes CSCP into five types to simplify diagnosis and guide treatment for better scrotal pain management.
Area of Science:
- Urology
- Pain Management
- Surgical Techniques
Background:
- Chronic scrotal content pain (CSCP) affects approximately 2.5% of urology outpatient visits.
- Etiology and pathophysiology of CSCP remain uncertain for general urologists.
- A simplified approach to CSCP diagnosis and treatment is needed.
Purpose of the Study:
- To provide a simplified diagnostic and treatment approach for CSCP.
- To subdivide CSCP into distinct clinical categories.
- To aid general urologists in managing scrotal pain.
Main Methods:
- Systematic literature review of PubMed, MEDLINE, and Cochrane databases.
- Keywords included "chronic scrotal content pain," "testicular pain," "orchialgia," and related terms.
- Inclusion of English language articles on CSCP diagnosis and treatment.
Main Results:
- CSCP was subdivided into 5 clinical presentation types based on pain location and associated symptoms.
- Treatment strategies were stepwise adjusted for each CSCP type.
- Pudendal neuralgia's role and nerve block options were detailed.
- Salvage treatments for microsurgical spermatic cord denervation failure were discussed, including cryoablation and Botox injections.
Conclusions:
- Subdivision of CSCP into distinct subtypes can enhance diagnostic accuracy.
- Categorization aids urologists in selecting appropriate treatment strategies for scrotal pain.
- This approach facilitates effective scrotal pain management in clinical practice.

