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Updated: May 10, 2025

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
Silver-Catalyzed Cascade Approach to Access Fused Pyrazolo-naphthyridine and -isoquinoline Backbones and
Fatemeh Abdiyan Mobarakeh1, Mohammad Rezaei-Gohar1, Kamran Amiri1
1Peptide Chemistry Research Institute, K. N. Toosi University of Technology, P.O. Box 15875-4416, Tehran, Iran.
Abstract:
We describe a novel approach for synthesizing diverse fused heterocyclic compounds by utilizing a sequential silver(I) catalyzed reaction between readily obtainable N-amidonaphthyridin ylide and dialkyl acetylenedicarboxylates. This method provides an efficient approach for the selective synthesis of tetracyclic ring-fused 1,6-naphthyridine and isoquinoline derivatives, offering exceptional structural diversity. In addition, the title compounds constitute an interesting class of luminophores with tunable emission solvatochromicity.
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