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Related Experiment Video

Updated: May 7, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

Targeted Axillary Dissection Using Surgical Marker Navigation after Neoadjuvant Systemic Treatment in Breast Cancer

Daniel Egle1, Christine Brunner1, Magdalena Ritter1

  • 1Department of Obstetrics and Gynaecology, Breast Cancer Center Tirol, Medical University of Innsbruck, Innsbruck, Austria.

Breast Care (Basel, Switzerland)
|April 21, 2025
PubMed
Summary

A new GPS-guided surgical marker navigation system achieved a 100% identification rate for targeted axillary dissection in early-stage breast cancer patients. This safe and effective method may reduce the need for extensive axillary lymph node dissection.

Keywords:
AxillaChemotherapyImaging techniqueMagneticsMargins of excisionNeoplasmNeoplasm gradingTherapy

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Single-port Non-liposuction Endoscopic Axillary Lymph Node Dissection in Breast Cancer Surgery
11:49

Single-port Non-liposuction Endoscopic Axillary Lymph Node Dissection in Breast Cancer Surgery

Published on: April 3, 2026

Area of Science:

  • Oncology
  • Surgical Oncology
  • Medical Devices

Background:

  • Accurate assessment of axillary lymph node involvement is crucial for early-stage breast cancer prognosis.
  • Targeted axillary dissection (TAD) is standard after neoadjuvant chemotherapy (NACT) for node-positive patients.
  • Reliable localization of marked target lymph nodes is essential to avoid unnecessary axillary lymph node dissection.

Purpose of the Study:

  • To evaluate the efficacy and safety of the Sirius Pintuition GPSDetect™ surgical marker navigation system.
  • To assess the feasibility of using magnetic guidance for localizing marked lymph nodes in breast cancer patients.

Main Methods:

  • Retrospective analysis of data from April 2022 to March 2023.
  • Inclusion of a consecutive series of patients with histologically confirmed axillary lymph node involvement before NACT.
  • Evaluation of the Sirius Pintuition GPSDetect™ system for surgical marker navigation.

Main Results:

  • The study included 20 patients with confirmed axillary lymph node involvement.
  • Surgical marker navigation using the Sirius Pintuition GPSDetect™ system demonstrated a 100% identification rate of the target node.
  • The procedure was found to be feasible and safe.

Conclusions:

  • Magnetically guided localization systems offer a viable alternative to traditional ultrasound-guided wire placement.
  • The Sirius Pintuition GPSDetect™ system's practicality may reduce treatment-related morbidity by preventing unnecessary axillary lymph node dissection.