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Updated: May 10, 2025

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management
Published on: March 15, 2024
Placement of Peripheral Nerve Stimulation Device in Single Limb Controls Long-Term Pain in Pediatric Patient With
Brandon Hou1, Yawar J Qadri2, Vipin Bansal1,3
1From the Department of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia.
Abstract:
Septic shock caused by Group A Streptococcus (GAS) can cause multiorgan failure and limb ischemia, necessitating amputations. We present a 17-year-old girl who survived GAS-induced septic shock but required quadruple amputations. Postoperatively, she experienced significant stump and phantom pain primarily in her left leg, posing challenges for pain management. Two percutaneous peripheral nerve stimulation (PNS) leads were implanted, targeting the left femoral and posterior sciatic nerves. This resulted in excellent long-term pain control, allowing for rapid weaning off systemic opioids and other analgesics. This report highlights PNS as an effective, minimally invasive alternative for managing chronic pain in pediatric patients.

