Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Low-Dose <sup>125</sup>I-Irradiation Enhances PRC1-Targeted NIS-CAR-T Cell Cytotoxicity Against Breast Cancer Cells.

Molecular imaging·2026
Same author

Carbonized Polymer Dots: A Class of Highly Functionalized Nanoparticles with Polymeric Characteristics.

Polymer science & technology (Washington, D.C.)·2026
Same author

Functionalized metallic nanomaterials, nanozymes and nanomotors for emerging tumor diagnosis and treatment: from design to theranostics strategies.

Theranostics·2026
Same author

Well-ST-seq: Cost-Effective and Near-Cellular Spatial Transcriptomics Using Deterministic Barcoded Bead Arrays.

Analytical chemistry·2026
Same author

Correction: Osteopromotive carbon dots promote bone regeneration through the PERK-eIF2α-ATF4 pathway.

Biomaterials science·2026
Same author

A conceptual blueprint for "turning cold to hot" in Osteosarcoma: from TME stratification hypotheses to adaptive therapeutic prospects.

Cell communication and signaling : CCS·2026

Related Experiment Video

Updated: May 10, 2025

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde
07:04

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde

Published on: November 11, 2022

2.3K

An Autonomously Liquefied Hydrogel Adhesive for Programmable Bioelectronic Interface.

Mengyuan Li1, Gongwei Tian2, Xuemei Jiang1

  • 1State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun, 130012, P.R. China.

Angewandte Chemie (International Ed. in English)
|April 21, 2025
PubMed
Summary

Researchers developed a new transient hydrogel adhesive for bioelectronics. This smart hydrogel offers programmable adhesion and autonomous detachment, simplifying device removal from hairy skin without damage.

Keywords:
Bioelectronic interfaceHydrogel adhesivesTransient hydrogels

More Related Videos

Bridging the Bio-Electronic Interface with Biofabrication
16:38

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

16.7K
Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells
10:14

Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells

Published on: November 18, 2016

6.4K

Related Experiment Videos

Last Updated: May 10, 2025

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde
07:04

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde

Published on: November 11, 2022

2.3K
Bridging the Bio-Electronic Interface with Biofabrication
16:38

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

16.7K
Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells
10:14

Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells

Published on: November 18, 2016

6.4K

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Bioelectronics Engineering

Background:

  • Hydrogel adhesives are crucial for drug delivery, regenerative medicine, and bioelectronics.
  • Detachment of hydrogel adhesives under benign conditions is essential for surgical repair and implanted devices.
  • Current stimuli-mediated detachment methods face challenges, especially for transient adhesives with programmable adhesion and autonomous detachment from substrates like hairy skin.

Purpose of the Study:

  • To develop a transient hydrogel adhesive with programmable adhesion and autonomous detachment capabilities.
  • To create a bioelectronic interface that ensures conformable and stable adhesion, even on hairy skin.
  • To enable easy and damage-free removal of bioelectronic devices after use.

Main Methods:

  • Utilized antagonistic enzyme reaction networks to drive the transient hydrogel adhesive.
  • Investigated tunable mechanical properties and adjustable adhesive strength of the hydrogel.
  • Demonstrated autonomous sol-gel-sol transition for programmable lifetime and detachment.
  • Evaluated the hydrogel's adhesion to various materials, including hairy skin.

Main Results:

  • The transient hydrogel adhesive exhibited tunable mechanical properties and adjustable adhesive strength.
  • Achieved autonomous sol-gel-sol transition, enabling a programmable lifetime and detachment.
  • Demonstrated conformable and stable adhesion to diverse materials, including hairy skin.
  • Bioelectrodes coated with the hydrogel successfully recorded high-quality electromyogram, electrocardiogram, and electroencephalogram signals on hairy skin without hair shaving.
  • Autonomous liquefaction allowed for easy, damage-free removal of bioelectrodes from hairy skin.

Conclusions:

  • The developed transient hydrogel adhesive offers programmable adhesion and autonomous detachment for bioelectronic interfaces.
  • This innovation facilitates stable and high-quality signal recording on hairy skin, simplifying bioelectronic device application and removal.
  • The study presents a novel approach for designing advanced hydrogel adhesives for conformable and detachable bioelectronic applications.