Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors01:20

Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors

388
Antiplatelet drugs emerge as frontline defenders against the insidious threat of thromboembolic diseases, where abnormal clots obstruct vital blood vessels. These drugs stand as bulwarks, inhibiting platelet aggregation and clot formation, thereby mitigating the risk of life-threatening conditions like myocardial infarction, coronary artery disease, and thrombotic strokes.
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
388
Assessment of the Cardiovascular System I: Subjective Data01:23

Assessment of the Cardiovascular System I: Subjective Data

241
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
241
Cardiovascular Drugs: Classification based on Therapeutic Indications01:18

Cardiovascular Drugs: Classification based on Therapeutic Indications

1.9K
Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However,...
1.9K
Preventive Healthcare Services01:30

Preventive Healthcare Services

943
Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
943
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

545
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
545
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

1.1K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Biological and Psychological Profiles of Hospital Healthcare Professionals During a Stressful Wartime.

Journal of general internal medicine·2026
Same author

Workability and Biological Biomarkers of Hospital Professionals during War.

QJM : monthly journal of the Association of Physicians·2026
Same author

Artificial intelligence improved efficiency of the computed tomography program.

Irish journal of medical science·2026
Same author

Endothelial function and cardiovascular disease in patients with rheumatoid arthritis.

Polish archives of internal medicine·2025
Same author

Sleep Deprivation and Endothelial Function.

The Israel Medical Association journal : IMAJ·2025
Same author

Genetic Links Between Depression and Heart Disease in Women.

The Israel Medical Association journal : IMAJ·2025

Related Experiment Video

Updated: May 10, 2025

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
23:33

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

Published on: February 28, 2012

83.3K

[CAN WE USE ASPIRIN AS A PRIMARY PREVENTION FOR CARDIOVASCULAR DISEASE?]

Arnon Blum1, Yehuda Shoenfeld2

  • 1Adelson Faculty of Medicine, Ariel University, and Laniado Hospital, Netanya Israel.

Harefuah
|April 21, 2025
PubMed
Summary
This summary is machine-generated.

Aspirin may help prevent cardiovascular disease (CVD) in adults aged 40-59 with high CVD risk. Benefits are unclear for those 60 and older, with no recommendation for primary prevention in this age group.

More Related Videos

Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells
13:38

Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells

Published on: January 18, 2017

12.2K
Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

4.7K

Related Experiment Videos

Last Updated: May 10, 2025

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
23:33

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

Published on: February 28, 2012

83.3K
Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells
13:38

Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells

Published on: January 18, 2017

12.2K
Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

4.7K

Area of Science:

  • Cardiology
  • Preventive Medicine
  • Clinical Trials

Context:

  • Aspirin has been historically considered for primary prevention of cardiovascular disease (CVD).
  • Recent clinical trials indicate that aspirin's efficacy for primary CVD prevention is contingent upon individual risk factors.
  • Current guidelines reflect a nuanced approach based on age and calculated CVD risk.

Purpose:

  • To summarize current evidence and guidelines regarding aspirin use for primary prevention of cardiovascular disease.
  • To delineate age-specific recommendations for aspirin initiation in CVD primary prevention.
  • To inform clinical decision-making based on updated research findings.

Summary:

  • Aspirin is recommended for primary prevention of CVD events in individuals aged 40 to 59 with a 10% or greater 10-year CVD risk.
  • For individuals aged 60 years and older, the benefits of aspirin for primary CVD prevention are less clear, and it is not generally recommended.
  • These recommendations are based on recent clinical trial data and updated guidelines, such as those from the USPSTF.

Impact:

  • Facilitates evidence-based prescribing of aspirin for primary CVD prevention.
  • Reduces potential harm from unnecessary aspirin use in older adults.
  • Contributes to personalized medicine approaches in cardiovascular health.