Related Experiment Video
Updated: May 10, 2025

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An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing
Published on: May 23, 2018
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Single-cell Epigenomic Profiling with High-throughput Droplet scChIP-seq
Justine Marsolier1,2, Eve Moutaux1,3, Kevin Grosselin4,5,6
1CNRS UMR3244, Institut Curie, PSL University, Paris, France.
Methods in Molecular Biology (Clifton, N.J.)
|April 21, 2025
Abstract:
Our high-throughput scChIP-seq approach combines droplet microfluidics with single-cell DNA barcoding to study the heterogeneity of epigenomes (H3K27me3, H3K4me3, H3K27Ac, H3K4me1) in a cellular population of several thousand cells with a coverage of up to 10,000 unique loci per cell.

