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Related Experiment Video

Updated: May 16, 2025

Inducement and Evaluation of a Murine Model of Experimental Myopia

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Published on: January 22, 2019

Large Language Models: Pioneering New Educational Frontiers in Childhood Myopia.

Mohammad Delsoz¹, Amr Hassan², Amin Nabavi¹

¹Hamilton Eye Institute, Department of Ophthalmology, University of Tennessee Health Science Center, 930 Madison Ave., Suite 471, Memphis, TN, 38163, USA.

Ophthalmology and Therapy

|April 21, 2025

Summary

ChatGPT-4o (o1 Preview) shows promise in creating high-quality patient education materials for childhood myopia, improving readability and accuracy. It also enhances existing online materials, making them more understandable and actionable for patients.

Keywords:

Childhood myopia Large language models Patient education materials

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Area of Science:

Artificial Intelligence in Healthcare
Medical Communication
Ophthalmology

Background:

Patient education materials (PEMs) are crucial for managing childhood myopia.
Evaluating the efficacy of large language models (LLMs) in generating and refining these materials is essential.

Purpose of the Study:

To assess the performance of ChatGPT-3.5, ChatGPT-4o (o1 Preview), and Google Gemini in creating and improving patient education materials on childhood myopia.
To evaluate the readability and quality of LLM-generated content using established metrics.

Main Methods:

Three prompts were used to generate and revise PEMs for childhood myopia.
LLM outputs were evaluated for quality (DISCERN), readability (FKGL, SMOG), understandability/actionability (PEMAT), and accuracy.
Statistical analysis was performed to compare model performance.

Main Results:

ChatGPT-4o (o1 Preview) and ChatGPT-3.5 produced good-quality PEMs, though quality slightly decreased with specific readability constraints.
All models generated understandable materials, but actionability remained below the target threshold.
Readability significantly improved with targeted prompts, with ChatGPT-4o (o1 Preview) showing the greatest gains.

Conclusions:

ChatGPT-4o (o1 Preview) is a capable tool for generating accurate, high-quality, and understandable patient education materials for childhood myopia.
LLMs can effectively improve the readability and quality of existing online patient education resources.