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Updated: May 12, 2025

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Rab32 regulates Golgi structure and cell migration through Protein Kinase A-mediated phosphorylation of Optineurin

Katherine M Johnson1,2, Maxwell G Marley1,2, Kristina Drizyte-Miller3

  • 1Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905.

Proceedings of the National Academy of Sciences of the United States of America
|April 21, 2025
PubMed
Summary

Rab32 protein regulates Golgi organization by anchoring Protein Kinase A (PKA). Disrupting this binding impairs Golgi structure and function, impacting cell migration and tumor invasion.

Keywords:
GolgiOptineurinProtein Kinase ARab32migration

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