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Updated: May 10, 2025
Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
Published on: May 9, 2022
Evaluating efficacy of laser-assisted new attachment procedure and adjunctive low-level laser therapy in treating
Fadime Kaya Dadas1,2, Selin Genc Kocaayan3, Mehmet Saglam3
1Katip Celebi University, Izmir, Turkey. fadimekayadadas@gmail.com.
Purpose:
This study aimed to evaluate the effectiveness of the laser-assisted new attachment procedure (LANAP) and low-level laser therapy (LLLT) on clinical, biochemical, and radiographic parameters when applied alongside scaling and root planing (SRP).
Methods:
The study was designed as a randomized controlled, single-blind, parallel trial involving 68 patients diagnosed with periodontitis. The participants were divided into three groups: Group 1: SRP (control), Group 2: LANAP, and Group 3: LLLT. Clinical measurements, gingival crevicular fluid (GCF) samples, and standard periapical radiographs were obtained pre-treatment and at one- and three-month follow-ups. In GCF, interleukin-1beta (IL-1β), interleukin-10 (IL-10), and vascular endothelial growth factor (VEGF) were analyzed.
Results:
In moderate (4-6 mm) and deep pockets (≥ 7 mm), laser-treated groups showed a significant reduction in pocket depth (PD) and clinical attachment level (CAL) compared to the control group. However, there were no statistically significant differences in biochemical markers between the groups. Group 2 demonstrated significant bone filling compared to the control group.
Conclusion:
In deep pockets, laser-treated groups provide additional benefits to SRP. The application of LLLT positively affected recession (REC).
Trial Registration Number:
NCT04694222 Date of registration: 01/01/2021.
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