Related Experiment Video

Updated: May 10, 2025

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
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Changes During Reopening in Premature Constriction or Closure of the Ductus Arteriosus: A Report of Two Cases

Daisuke Katsura1, Ayako Inatomi1, Shinsuke Tokoro1

  • 1Department of Obstetrics and Gynecology, Shiga University of Medical Science, Otsu, JPN.

Cureus
|April 22, 2025
PubMed

Although premature constriction or closure of the ductus arteriosus (PCDA) is associated with poor prognosis and early delivery is considered before deterioration occurs, some cases may improve and have a good prognosis, but the changes in fetal Doppler during the reopening of the ductus arteriosus are unclear, as are the factors related to its reopening. We encountered two cases of PCDA. In the first case, right cardiac function and ductus venosus flow normalized in a few days and the ductus arteriosus reopened spontaneously, and became vaginal delivery at 37 weeks of gestation. In the second case, labor induction was performed due to confirmed fetal cardiac stress associated with the closure of the ductus arteriosus at 38 weeks of gestation, and cesarean section was performed due to non-reassuring fetal status. The improvement in the right ventricular myocardial performance index, ductus venosus pulsatility index, the tendency for ductus arteriosus diastolic velocity to decrease, and confirmation of prograde flow into the pulmonary artery within a few days could serve as predictive indicators for the reopening of the ductus arteriosus.

Keywords:
closureconstrictionductus arteriosus diastolic velocityductus venosus pulsatility indexreopening of ductus arteriosusright ventricular myocardial performance indexthe ductus arteriosus

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