Related Experiment Video
Updated: May 10, 2025

04:08
Metacarpal Small Incision for Carpal Tunnel Syndrome
Published on: April 5, 2024
326
Exploring Subtypes Based on Depression and Anxiety in Preoperative Patients With Carpal Tunnel Syndrome: A Two-Step
Akihito Yoshida1, Katsuyuki Iwatsuki2, Takaaki Shinohara3
1Department of Integrated Health Sciences, Graduate School of Medicine, Nagoya University, Nagoya City, JPN.
Cureus
|April 22, 2025
Summary
Preoperative depression and anxiety significantly impact carpal tunnel syndrome (CTS) outcomes. Identifying psychological subgroups in CTS patients pre-surgery can reveal those with greater disability.
Area of Science:
- Orthopedics
- Psychiatry
- Rehabilitation Medicine
Background:
- Growing evidence highlights the importance of depression and anxiety in patient care.
- These psychological factors are often overlooked in clinical guidelines for carpal tunnel syndrome (CTS).
Purpose of the Study:
- To classify patients with carpal tunnel syndrome (CTS) into preoperative subgroups.
- To analyze these subgroups using depression and anxiety scales.
- To compare outcomes across identified patient clusters.
Main Methods:
- Utilized K-means cluster analysis on Japanese versions of the Self-Rating Depression Scale (SDS) and Pain Anxiety Symptom Scale-20 (PASS-20) for 65 CTS patients.
- Employed Ward's method for grouping psychological parameters.
- Compared sociodemographic, disease-related, physical, psychological, and disability outcomes between clusters.
Main Results:
- A three-cluster solution was identified: 'psychologically normal,' 'only depression,' and 'psychologically impaired.'
- The 'psychologically impaired' cluster exhibited more severe upper extremity disability compared to other groups.
- This indicates distinct psychological profiles influencing CTS patient outcomes.
Conclusions:
- This study provides evidence for identifying depression and anxiety in carpal tunnel syndrome patients during the preoperative period.
- Recognizing these psychological factors can aid in personalized treatment strategies.
- Preoperative psychological assessment is crucial for managing CTS effectively.

