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Updated: May 10, 2025

Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes
Published on: September 8, 2013
Thiocyanate: a visible-light-driven traceless auxiliary for stereoselective cyclopropyl ketone construction
Subhashis Mondal1, Shyamal Pramanik1, Soumitra Maity1
1Department of Chemistry and Chemical Biology, Indian Institute of Technology (ISM), Dhanbad, Jharkhand 826004, India. smaity@iitism.ac.in.
Abstract:
An operationally simple method for the diastereoselective construction of cyclopropyl ketones from alkenes is described in this study. The pseudohalide -SCN is used as a traceless auxiliary to address the elimination problem posed by halide intermediates, leading to the successful incorporation of single-electron-withdrawing-group-substituted radical progenitors in the cyclopropanation manifold.
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