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Updated: May 14, 2025

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High Throughput, Real-time, Dual-readout Testing of Intracellular Antimicrobial Activity and Eukaryotic Cell Cytotoxicity
Published on: November 16, 2016
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A membrane-penetrative COF-based nanoplatform for intracellular bacterial pathogen eradication across diverse niches
Abstract:
A COF-based therapeutic nanoplatform has been developed that can be transported to intracellular bacteria-located regions in the host cells, where ultrasound irradiation triggered ROS generation, membrane-penetrative NO release, and the production of highly reactive peroxynitrite (ONOO-), enabling effective bacteria eradication across diverse niches.
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