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IridiumIII Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II
Published on: July 7, 2015
Harnessing the power of iridium AIEgens for NAD(P)H detection in aqueous medium and living cells
Ajay Gupta1, Aryan Gautam1, Smaranika Patra1
1School of Physical Sciences, Jawaharlal Nehru University, New Delhi 110067, India. pijus@jnu.ac.in.
Abstract:
A rationally designed luminescent probe based on cyclometalated iridium(III) AIEgens was developed for the rapid, sensitive, and specific detection of NAD(P)H in aqueous media. This probe was successfully utilized for bioimaging of NADH within the mitochondria of living cancer cells, highlighting its potential as a valuable tool for investigating NADH-associated cellular processes.
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