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Amniotic fluid embolism in late second trimester abortion: a case report
Melissa L Wong1, Erica Holland2, Katharine O White2
1Montefiore Medical Center, Albert Einstein College of Medicine, New York, New York, USA.
Summary
Amniotic fluid embolism (AFE) is a rare pregnancy complication. This case highlights AFE during a second-trimester abortion, emphasizing the need for awareness and timely diagnosis in such critical scenarios.
Area of Science:
- Obstetrics and Gynecology
- Maternal-Fetal Medicine
- Critical Care Medicine
Background:
- Amniotic fluid embolism (AFE) is a rare, life-threatening obstetric emergency.
- Limited data exists on AFE during the second trimester or abortion procedures.
- Management guidelines for AFE in these specific settings are scarce.
Purpose of the Study:
- To report a case of amniotic fluid embolism (AFE) occurring during a second-trimester induced abortion.
- To highlight the diagnostic challenges and management of AFE in this underreported context.
Main Methods:
- Case presentation of a 32-year-old woman undergoing induced abortion at 24 weeks' gestation.
- Clinical management included resuscitation, completion of the procedure, and uterine artery embolization for hemorrhage.
- Diagnosis of AFE was based on cardiovascular collapse and disseminated intravascular coagulation (DIC) disproportionate to blood loss.
Main Results:
- The patient experienced hypoxia and pulseless electrical activity during dilation and evacuation.
- Return of spontaneous circulation (ROSC) was achieved following resuscitation.
- The patient recovered with transient short-term memory loss, with AFE diagnosed as the primary complication.
Conclusions:
- AFE should be considered in cases of acute collapse during pregnancies over 20 weeks gestation, particularly during abortion procedures.
- Abortion restrictions may lead to delayed care, potentially increasing gestational age and the incidence of AFE.
- Further research is needed on the impact of abortion restrictions on maternal mortality and morbidity, with AFE and thromboembolism as key considerations.

