Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vector Representation of Complex Numbers01:16

Vector Representation of Complex Numbers

84
Complex numbers, represented in Cartesian coordinates, can also be visualized as vectors. These vectors can be expressed in polar form, emphasizing their magnitude and angle. When a complex number is input into a function, the output is another complex number, highlighting the function's zero point from which the vector representation can originate.
Consider a function defined as the product of the complex factors in the numerator divided by the product of the complex factors in the...
84
Complexation Equilibria: Overview01:23

Complexation Equilibria: Overview

567
Complexation reactions take place when dative or coordinate covalent bonds form between metal ions and ligands. The compounds formed in these reactions are called coordination compounds. The number of bonds formed between the metal ion and the ligands is called its coordination number. Generally, most metal ions in an aqueous solution are solvated by water molecules and thus exist as aqua complexes.
The equilibrium constant of the complexation reaction is represented as the formation constant...
567
Ladder Diagrams: Complexation Equilibria01:07

Ladder Diagrams: Complexation Equilibria

291
Ladder diagrams are useful for evaluating equilibria involving metal-ligand complexes. The vertical scale of the ladder diagram represents the concentration of unreacted or free ligand, pL. The horizontal lines on the scale depict the log of stepwise formation constants for metal-ligand complexes and indicate the dominant species in all the regions.
The formation constant, K1, for the formation of Cd(NH3)2+ complex from cadmium and ammonia is 3.55 × 102. Log K1 (i.e. pNH3) is 2.55, and...
291
Complex Power01:14

Complex Power

339
Power engineers have introduced the concept of complex power to determine the cumulative effect of parallel loads. This idea plays a crucial role in power analysis because it encompasses all the details related to the power consumed by a specific load.
Complex power is defined as the multiplication of the voltage and the complex conjugate of the current. The magnitude of this power, known as apparent power, is measured in volt-amperes (VA). Notably, the angle of the complex power equates to the...
339
Complexation Equilibria: Factors Influencing Stability of Complexes01:09

Complexation Equilibria: Factors Influencing Stability of Complexes

297
In complexation reactions, metal cations are the electron pair acceptors, and the ligands are the electron pair donors. The stability of the metal complexes depends primarily on the complexing ability of the central metal ion and the nature of the ligands. Generally, the complexing ability of the metal ion depends on the size and charge of the ion. As the metal ion size increases, the stability of the metal complexes decreases, provided that the valency of the metal ion and the ligands remain...
297
Equivalent Capacitance01:19

Equivalent Capacitance

290
From the study of resistive circuits, it is understood that employing a series-parallel combination serves as an effective strategy for simplifying circuits. Capacitors can be arranged within a circuit in one of two ways: a series configuration or a parallel configuration. The way these capacitors are connected to a battery will influence both the potential drop across each individual capacitor and the size of the charge that each capacitor can store. This is determined by the specific type of...
290

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Designer binders.

Science signaling·2026
Same author

Cholinergic signals and antibodies.

Science signaling·2026
Same author

SIRT2 versus Lck.

Science signaling·2026
Same author

Ca<sup>2+</sup>-driven E3 ligase activity.

Science signaling·2025
Same author

STING's cysteine modifications.

Science signaling·2025
Same author

Tailored receptor modulators.

Science signaling·2025
Same journal

ZNRF3 and RNF43 are active monomeric E3 ubiquitin ligases that self-associate.

Science signaling·2026
Same journal

Allosteric ligands with distinct properties uncover tissue-specific physiological regulation mediated by free fatty acid receptor 2.

Science signaling·2026
Same journal

Diacylglycerol kinase ζ in B lymphocytes supports CD40-mediated immune synapse formation, mTORC1 signaling, and plasma cell fate.

Science signaling·2026
Same journal

The APC/C adaptor Cdh1 stabilizes STING to potentiate innate immune activation in renal cell carcinoma.

Science signaling·2026
Same journal

Fattening mother's milk with oxytocin.

Science signaling·2026
Same journal

Virion display reveals MD-1 as an endogenous agonist for the orphan receptor GPRC5B.

Science signaling·2026
See all related articles

Related Experiment Video

Updated: May 10, 2025

The MultiBac Protein Complex Production Platform at the EMBL
13:51

The MultiBac Protein Complex Production Platform at the EMBL

Published on: July 11, 2013

15.9K

Making complexes less complicated.

John F Foley1

  • 1Science Signaling, AAAS, Washington, DC 20005, USA.

Science Signaling
|April 22, 2025
PubMed
Summary
This summary is machine-generated.

A new proteomics method offers deeper insights into breast cancer. This approach enhances our understanding of the breast cancer proteome for improved diagnostics and treatments.

More Related Videos

Synthesis of a Water-soluble Metal&#8211;Organic Complex Array
06:40

Synthesis of a Water-soluble Metal–Organic Complex Array

Published on: October 8, 2016

9.8K
Multimer-PAGE: A Method for Capturing and Resolving Protein Complexes in Biological Samples
07:40

Multimer-PAGE: A Method for Capturing and Resolving Protein Complexes in Biological Samples

Published on: May 5, 2017

11.3K

Related Experiment Videos

Last Updated: May 10, 2025

The MultiBac Protein Complex Production Platform at the EMBL
13:51

The MultiBac Protein Complex Production Platform at the EMBL

Published on: July 11, 2013

15.9K
Synthesis of a Water-soluble Metal&#8211;Organic Complex Array
06:40

Synthesis of a Water-soluble Metal–Organic Complex Array

Published on: October 8, 2016

9.8K
Multimer-PAGE: A Method for Capturing and Resolving Protein Complexes in Biological Samples
07:40

Multimer-PAGE: A Method for Capturing and Resolving Protein Complexes in Biological Samples

Published on: May 5, 2017

11.3K

Area of Science:

  • Biochemistry
  • Oncology
  • Proteomics

Background:

  • The proteome of breast cancer remains incompletely characterized.
  • Advanced proteomic techniques are crucial for understanding cancer biology.

Purpose of the Study:

  • To present a novel blended proteomics platform.
  • To achieve greater depth in analyzing the breast cancer proteome.

Main Methods:

  • Integration of multiple proteomic technologies.
  • Application of the platform to breast cancer samples.

Main Results:

  • The blended platform identified a significantly larger number of proteins compared to single methods.
  • New insights into the complexity of the breast cancer proteome were obtained.

Conclusions:

  • The developed blended proteomics platform provides unprecedented depth for breast cancer proteome analysis.
  • This enhanced understanding can facilitate the discovery of new biomarkers and therapeutic targets for breast cancer.