Related Experiment Video
Updated: May 10, 2025
Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Auditory and cognitive abilities in patients with chronic kidney disease: a comparative study across stages
Tuana Saglanmak1, Aysenur Kucuk Ceyhan2
1Department of Audiology, Faculty of Health Sciences, Istanbul Aydin University, Istanbul, Turkey.
Background:
The impact of chronic kidney disease (CKD) on peripheral hearing is well documented, but little is known about the impact on auditory processing.
Aim:
This study aimed to evaluate auditory processing and cognitive abilities in CKD and to assess changes according to the disease phases.
Materials And Methods:
Eighty-nine CKD patients, aged 25-65 (48 study and 41 control) with stages 2-4, participated. Random Gap Detection Test (RGDT), Frequency Pattern Test (FPT), Duration Pattern Test (DPT), the Digit Span Backward Task (DSBT) and the speech discrimination (SD) in noise and in quiet test were employed.
Results:
The comparison between the two groups indicated significant decreases in test scores for the RGDT, FPT, DPT, DSBT, and SD (in noise) within in the group with CKD (p < .001). The SD (in quiet) test exhibits no difference. There were no significant variations in any evaluated parameter between CKD stages.
Conclusions And Significance:
The results indicate that CKD can impair auditory and cognitive processing, hence affecting SD, especially in challenging auditory environments. Nevertheless, no significant changes were observed across the phases of CKD, suggesting that impairments in these capacities may appear early in the course of the disease.
Related Concept Videos
01:17Factors Affecting Renal Clearance: Renal Impairment
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
01:11Renal Failure: Dose Adjustments
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
01:10Nephrons
01:30Cognitive Development During Adulthood
01:27Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
01:45Kidney Structure