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Breaking the code: Using the Precision Health Model to guide research and clinical care
Marilyn J Hammer1, Yvette P Conley2, Wendy A Henderson3
1Department of Nursing and Patient Care Services and Department of Medical Oncology, Division of Population Sciences, Dana-Farber Cancer Institute, Boston, MA.
Background:
Precision health is a person-centered approach to health and well-being that is operationalized through evaluating omics-level profiles and their associations with the exposome. A precision health approach addresses the challenge that "one size does not fit all" in the management of an individual's health.
Purpose:
The purpose of this white paper is to introduce a Precision Health Model and its application in research and clinical care.
Methods:
An expert panel reviewed and synthesized the extant literature related to precision health, the current state of omics' science, and common exposome factors that influence the health/illness continuum. A case study provides the framework for the application of the Precision Health Model.
Discussion:
Precision health and key domains are defined and serve as the platform for the development of the Precision Health Model.
Conclusion:
Application of the Precision Health Model will provide inclusive, equitable, person-centered research and clinical care.
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