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Severe strongyloidiasis presenting as occult gastro-intestinal tract malignancy
Annals of Tropical Medicine and Parasitology
|June 1, 1985
Summary
Strongyloides stercoralis infection caused severe gastrointestinal symptoms in a patient initially suspected of having colon cancer. Prompt treatment with levamisole resolved the infection and symptoms, leading to significant weight gain.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Parasitology
Background:
- Colonic malignancy is a significant concern in patients presenting with altered bowel habits and rectal bleeding.
- Strongyloidiasis is a parasitic infection caused by the nematode Strongyloides stercoralis, often presenting with diverse gastrointestinal symptoms.
Observation:
- A 38-year-old male presented with severe weight loss, alternating diarrhea and constipation, and hematochezia.
- Initial clinical suspicion pointed towards colonic malignancy, necessitating further investigation.
- Microscopic examination of stool revealed numerous Strongyloides stercoralis larvae.
Findings:
- The patient's symptoms were attributed to Strongyloides stercoralis infection, not colonic malignancy.
- Treatment with levamisole resulted in a rapid and complete cessation of all gastrointestinal symptoms.
- The patient experienced substantial weight recovery following successful antiparasitic therapy.
Implications:
- This case highlights the importance of considering parasitic infections, such as strongyloidiasis, in the differential diagnosis of unexplained gastrointestinal symptoms, even when malignancy is suspected.
- Levamisole is an effective treatment option for Strongyloides stercoralis infection, leading to favorable patient outcomes.
- Accurate diagnosis and timely treatment of strongyloidiasis are crucial for preventing prolonged morbidity and ensuring complete patient recovery.