Racial Disparities in Hypertension-Related Hospital Mortality Among Adults in the United States

Gideon U Noah1, Mercy U Omohoro2, Hezborn M Magacha3

  • 1Internal Medicine, Center of Excellence in Inflammation, Infectious Disease, and Immunity, East Tennessee State University, Johnson City, USA.

Cureus
|April 23, 2025
PubMed

Insights

Black patients face significantly higher in-hospital mortality rates from hypertension compared to White patients. This study highlights critical racial disparities in hypertension outcomes, emphasizing the need for equitable healthcare access and culturally sensitive policies to reduce mortality.

Area of Science:

  • Public Health
  • Health Disparities
  • Cardiovascular Disease Epidemiology

Background:

  • Hypertension is a leading cause of hospital admissions and mortality globally and in the U.S.
  • Racial disparities in healthcare contribute to unequal outcomes, including hypertension-related in-hospital mortality.
  • Systemic inequalities, policy implementation, access to care, and socioeconomic factors exacerbate these disparities.

Purpose of the Study:

  • To investigate the extent of racial disparities in hypertension-related in-hospital mortality among adults in the United States.
  • To analyze the association between race and in-hospital mortality for hypertension-related admissions.

Main Methods:

  • Utilized data from the Healthcare Cost and Utilization Project's (HCUP) National Inpatient Sample (NIS) from 2016 to 2022.
  • Included 360,642 adult patients hospitalized for hypertension-related issues.
  • Employed descriptive, bivariate, and multivariate analyses, adjusting for confounders like age, sex, hospital location, insurance, and diabetes.

Main Results:

  • Significant racial disparities in hypertension-related in-hospital mortality were observed.
  • Black patients exhibited higher mortality rates (55%) compared to White patients (OR=1.55, 95% CI=1.42,1.69, p<0.0001).

Conclusions:

  • This study confirms substantial racial disparities in hypertension-related hospital mortality, with Black individuals facing disproportionately higher risks.
  • Addresses the urgent need for targeted interventions to combat health inequities in hypertension care.
  • Recommends enhancing access to quality care, culturally sensitive healthcare delivery, and policy reforms to improve outcomes.

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