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The Relationship Between Postpartum Depression and Timely Child Vaccination: A Systematic Review
Julien Robitaille1, Kayla Esser1, Catherine King2
1Centre for Vaccine Preventable Disease, Dalla Lana School of Public Health, University of Toronto, Toronto, ON M5T 3M7, Canada.
Vaccines
|April 23, 2025
Summary
Postpartum depression (PPD) may impact timely childhood vaccinations, but research findings are mixed. More studies are needed to understand if parents with PPD require specific support for child immunization schedules.
Area of Science:
- Public Health
- Pediatrics
- Mental Health
Background:
- Childhood vaccination success depends on caregiver awareness, willingness, and ability.
- Postpartum depression (PPD) may hinder parents' capacity for essential preventive care, including vaccinations.
Purpose of the Study:
- To systematically review the existing literature on the association between postpartum depression and timely childhood vaccinations.
Main Methods:
- A comprehensive systematic search of eight major databases was conducted up to September 2023.
- Included primary studies examining the PPD-vaccination link in children aged 0-24 months.
- Data extraction and quality assessment were performed independently by two researchers.
Main Results:
- Twelve studies met eligibility criteria, with most originating from high-income countries.
- Half of the studies (6/12) indicated a link between maternal PPD and delayed child vaccinations; the other half found no association.
- High-quality studies showing a relationship reported a small magnitude of absolute risk.
Conclusions:
- Significant heterogeneity exists in current research on PPD and child vaccination timeliness.
- Further high-quality research with standardized definitions is necessary.
- Tailored strategies and support may be required for parents experiencing PPD to overcome vaccination barriers.
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