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Updated: May 10, 2025

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Fatigue Scale for Children With Cancer: A Systematic Review and Reliability Generalization Meta-analysis

Hyejung Lee1, Yoojin Kim2, Sumi Oh3

  • 1College of Nursing, Mo-Im Nursing Research, Yonsei University, Seodaemun-gu, Seoul, Korea.

Seminars in Oncology Nursing
|April 23, 2025
PubMed

Insights

The Fatigue Scale demonstrates high reliability for assessing fatigue in pediatric cancer patients. Factors like leukemia/lymphoma diagnosis and language translation can influence results, requiring careful interpretation.

Area of Science:

  • Pediatric Oncology
  • Psychometrics
  • Clinical Assessment

Background:

  • Fatigue is a common and debilitating symptom in pediatric oncology patients.
  • The Fatigue Scale is the most frequently used instrument to measure fatigue severity in this population.
  • Understanding the reliability of the Fatigue Scale is crucial for accurate assessment and intervention.

Purpose of the Study:

  • To evaluate the overall reliability of the Fatigue Scale in pediatric oncology.
  • To identify factors that may influence the reliability estimates of the Fatigue Scale.

Main Methods:

  • A systematic literature search was conducted across multiple databases (PubMed, CINAHL, PsycINFO, Medline, Scopus, Embase, Google Scholar).
  • Reliability generalization meta-analyses were performed on data from 21 selected studies, encompassing 3,750 patients.
  • A random-effects model was used to analyze Cronbach's alpha values.

Main Results:

  • The Fatigue Scale demonstrated high overall reliability, with a mean weighted effect size of 0.915.
  • Leukemia/lymphoma diagnosis was a significant moderator in parent-reported reliability.
  • Non-English language use significantly moderated reliability in both parent and staff samples.

Conclusions:

  • The Fatigue Scale is a reliable instrument for assessing fatigue in diverse pediatric oncology populations.
  • Clinicians and researchers can confidently use the Fatigue Scale to guide interventions for fatigue relief.
  • Consideration of specific factors like cancer type and language is important for interpreting scale results.
Abstract

Keywords:
Cancer-related fatigueChildrenFatigue scaleMeta-AnalysisReliability generalisation

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