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An efficient fine tuning strategy of segment anything model for polyp segmentation
Mingyan Wang1, Cun Xu2, Kefeng Fan3
1Information Technology Center, Tsinghua University, Beijing, 100084, China. wangmingyan@tsinghua.edu.cn.
Scientific Reports
|April 24, 2025
Summary
This study introduces PSF-SAM, an efficient method for segmenting colon polyps. It overcomes limitations of standard fine-tuning, improving accuracy and few-shot learning for better colon cancer detection.
Area of Science:
- Medical imaging
- Artificial intelligence in healthcare
- Gastroenterology
Background:
- Colon cancer is a global health concern, necessitating accurate and cost-effective detection methods.
- Colon polyp segmentation is crucial for early diagnosis, but faces challenges like high annotation costs and limited accuracy.
- Existing fine-tuning methods for models like Segment Anything Model (SAM) can lead to catastrophic forgetting, hindering generalization.
Purpose of the Study:
- To propose and evaluate an efficient fine-tuning strategy for SAM to improve colon polyp segmentation.
- To address the problem of catastrophic forgetting in SAM during fine-tuning for medical imaging tasks.
- To enhance the performance of colon polyp segmentation, particularly in few-shot learning scenarios.
Main Methods:
- Developed PSF-SAM, an efficient fine-tuning method for SAM by freezing most parameters and optimizing specific structures.
- Applied PSF-SAM to colon polyp segmentation tasks.
- Evaluated performance using metrics such as mDice coefficients and mIoU on Kvasir-SEG and CVC-ClinicDB datasets.
Main Results:
- PSF-SAM demonstrated superior performance compared to conventional fine-tuning methods on colon polyp segmentation.
- The proposed method significantly improved accuracy, as indicated by higher mDice and mIoU scores.
- PSF-SAM showed notable advantages in few-shot learning scenarios, outperforming existing techniques.
Conclusions:
- PSF-SAM effectively mitigates catastrophic forgetting and enhances colon polyp segmentation accuracy.
- The proposed efficient fine-tuning strategy offers a promising solution for improving colon cancer detection through medical image analysis.
- PSF-SAM presents a valuable advancement for few-shot learning in medical segmentation tasks.

