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Updated: May 10, 2025

Author Spotlight: Efficiently Eliminating Bacteriophages from Infected Salmonella Cultures Using Lipopolysaccharides
Published on: June 28, 2024
Bacteriophage application in inhibiting corrosion- producing bacteria
Guangming Zhang1, Zisheng Guo1, Shuo Liu1
1Key Laboratory of Resources Biology and Biotechnology in Western China, Provincial Key Laboratory of Biotechnology of Shaanxi Province, the College of Life Sciences, Ministry of Education, Northwest University, Xi'an, 710069, China.
Abstract:
Sulfate-reducing bacteria (SRB) are a major cause of microbially-induced corrosion (MIC) and souring (MIS), leading to significant challenges in industries like oil recovery and wastewater treatment. Due to SRB's resistance to antimicrobial agents, bacteriophage (phage) therapy offers a promising alternative for SRB control. In this study, a novel lytic phage, SRB7757, targeting Desulfovibrio vulgaris, was isolated from sewage. SRB7757 inhibited sulfide production by 92.3% within 24 h and significantly reduced corrosion on metal specimens after 28 days, highlighting its potential in controlling MIC and MIS. Genome analysis revealed SRB7757 has a genome size of 142,573 bp, 217 ORFs, and 6 tRNAs, and belongs to the Chaseviridae family. SRB7757 exhibits a latent period of 4 h, a burst size of ~ 100 PFU/cell, and is stable between 4 °C and 60 °C across a pH range of 2.0-12.0. Two predicted lytic enzymes of SRB7757 demonstrated higher inactivation and biofilm removal rates.
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