Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Individual alcohol reaction profiles.

I Lehtinen, T Nyrke, A Lang

    Alcohol (Fayetteville, N.Y.)
    |May 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Differential susceptibility of Candida (Candidozyma) auris clades to surface disinfectants.

    The Journal of hospital infection·2025
    Same author

    Refined high-content imaging-based phenotypic drug screening in zebrafish xenografts.

    NPJ precision oncology·2023
    Same author

    KDM6A mutations promote acute cytoplasmic DNA release, DNA damage response and mitosis defects.

    BMC molecular and cell biology·2021
    Same author

    Diversity at the core of all our work!

    Laboratory animals·2021
    Same author

    Fire safety and emergency evacuation guidelines for intensive care units and operating theatres: for use in the event of fire, flood, power cut, oxygen supply failure, noxious gas, structural collapse or other critical incidents: Guidelines from the Association of Anaesthetists and the Intensive Care Society.

    Anaesthesia·2021
    Same author

    Combining segmental bulk- and single-cell RNA-sequencing to define the chondrocyte gene expression signature in the murine knee joint.

    Osteoarthritis and cartilage·2021

    Individual responses to alcohol (ethanol) are repeatable, varying significantly between people. Researchers recommend assessing ethanol sensitivity using a comprehensive reaction profile, not just single measures.

    Area of Science:

    • Neuroscience
    • Pharmacology
    • Human Physiology

    Background:

    • Ethanol (alcohol) consumption elicits diverse physiological and psychological effects.
    • Understanding interindividual variability in acute alcohol responses is crucial for public health and clinical applications.

    Purpose of the Study:

    • To investigate and characterize the interindividual differences in acute reactions to ethanol.
    • To determine if individual responses to ethanol are consistent over time.

    Main Methods:

    • A double-blind, controlled experiment involving six healthy female subjects.
    • Standardized intravenous ethanol infusion to achieve a target blood alcohol concentration (BAC) of 1 mg/ml within 1 hour.
    • Repeated measurements of electroencephalogram (EEG) spectra, smooth pursuit eye movements, mood states, and BAC over a 4-hour period.

    Related Experiment Videos

    Main Results:

    • Subjects exhibited a consistent, individual reaction profile to ethanol.
    • Key indicators of this profile included changes in alpha mean frequency (EEG), theta band power (EEG), corrective eye movements, and subjective intoxication.
    • A high degree of repeatability was observed in these individual response patterns.

    Conclusions:

    • Ethanol sensitivity is best described by a multi-faceted reaction profile rather than a single physiological or psychological variable.
    • Individual response patterns to acute ethanol exposure are reliable and distinct.
    • Further research should focus on characterizing these individual profiles to better understand alcohol's effects.