Intrinsic capacity trajectories and cardiovascular disease incidence among Chinese older adults: a population-based prospective cohort study
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.Declining intrinsic capacity (IC) in older adults is linked to a higher risk of cardiovascular diseases (CVD). Identifying these trajectories is key for healthy aging and CVD prevention strategies.
Area Of Science
- Gerontology and Public Health
- Cardiovascular Disease Epidemiology
- Aging Research
Background
- Intrinsic capacity (IC), encompassing physical and mental abilities, is a crucial indicator of healthy aging.
- The relationship between evolving IC and the development of cardiovascular diseases (CVD) in older populations requires further investigation.
Purpose Of The Study
- To define distinct trajectories of intrinsic capacity (IC) over time in older adults.
- To examine the association between identified IC trajectories and the incidence of cardiovascular diseases (CVD).
Main Methods
- A prospective cohort study utilizing data from the China Health and Retirement Longitudinal Study (CHARLS) from 2011 to 2020.
- Intrinsic capacity (IC) was assessed across five domains (locomotion, sensory, vitality, cognition, psychology) using the WHO framework.
- Group-based trajectory modeling identified IC patterns, while Cox proportional hazard models analyzed CVD incidence risk.
Main Results
- Three distinct IC trajectories were identified: moderate with increase (61.3%), low with slow decline (27.61%), and high with decline (11.09%).
- Individuals in the 'low IC with slow decline' group showed a 1.68 times higher likelihood of developing CVD compared to the 'high IC with decline' group.
- The study included 3,336 older adults without baseline CVD, with an average follow-up of 6.78 years.
Conclusions
- Intrinsic capacity (IC) trajectories in Chinese older adults are diverse.
- A pattern of low intrinsic capacity with a slow decline is significantly associated with an elevated risk of incident cardiovascular diseases (CVD).
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
Related Concept Videos
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
There are four defined lung volume measures: tidal volume, inspiratory reserve volume, expiratory reserve volume, and residual volume.
Tidal volume is the amount of air inhaled and exhaled in a normal breath. Inspiratory...
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to...