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Selective Lower-Occupied Through-Bond Interactions for Efficient Organic Phosphorescence Enabling High-Resolution
Rajashekhar K Mulimani1, Sakuya Ueda1, Ryo Miyashita1
1Department of Engineering Science, The University of Electro-Communications, 1-5-1 Chofugaoka, Chofu, Tokyo, 182-8585, Japan.
Advanced Materials (Deerfield Beach, Fla.)
|April 24, 2025
Summary
Researchers developed a novel molecule for efficient red organic persistent room-temperature phosphorescence (RTP). This breakthrough enables high-resolution, long-wavelength afterglow bioimaging and multicolor imaging applications.
Area of Science:
- Materials Science
- Chemistry
- Biomedical Imaging
Background:
- Persistent organic room-temperature phosphorescence (RTP) is crucial for high-resolution bioimaging, overcoming autofluorescence limitations.
- Low yield of organic RTP in the long-wavelength spectrum restricts detailed imaging and multicolor capabilities.
Purpose of the Study:
- To develop a molecule exhibiting efficient red RTP with high yield, suitable for long-wavelength bioimaging.
- To investigate molecular design strategies for enhancing long-wavelength phosphorescence through controlled intermolecular interactions.
Main Methods:
- Synthesis of novel organic molecules featuring red phosphorescent chromophores substituted with phenylthio groups.
- Characterization of RTP properties, including yield and lifetime, in a crystalline host medium.
- Analysis of intermolecular interactions (through-bond and through-space) influencing phosphorescence efficiency.
Main Results:
- A molecule achieved a high RTP yield of 46.3% and a lifetime of 0.43 s.
- Selective intermolecular interactions significantly boosted long-wavelength phosphorescence.
- Efficient red RTP enabled bright red afterglow from individual nanoparticles.
Conclusions:
- The developed molecule provides a high-performance red RTP dye for advanced bioimaging.
- Tuning intermolecular interactions is a viable strategy for designing novel RTP materials.
- This work paves the way for high-resolution, full-color afterglow imaging.
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