Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mutation, Gene Flow, and Genetic Drift01:09

Mutation, Gene Flow, and Genetic Drift

57.5K
In a population that is not at Hardy-Weinberg equilibrium, the frequency of alleles changes over time. Therefore, any deviations from the five conditions of Hardy-Weinberg equilibrium can alter the genetic variation of a given population. Conditions that change the genetic variability of a population include mutations, natural selection, non-random mating, gene flow, and genetic drift (small population size).
57.5K
Genetic Screens02:46

Genetic Screens

4.8K
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
4.8K
Mismatch Repair01:20

Mismatch Repair

4.6K
Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
4.6K
In-vitro Mutagenesis01:16

In-vitro Mutagenesis

13.6K
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
13.6K
What is Population Genetics?01:25

What is Population Genetics?

56.9K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
56.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Text-Based Classification of Mitral Valve Disease Severity from Echocardiography Reports.

Studies in health technology and informatics·2026
Same author

Improved analytical workflow towards machine learning supported N-glycomics-based biomarker discovery.

Talanta·2025
Same author

Classifying Type 2 Diabetes Using N-Glycan Profiling and Machine Learning Algorithms.

Studies in health technology and informatics·2025
Same author

Sensitivity Analysis of Long Short-Term Memory-Based Neural Network Model for Vehicle Yaw Rate Prediction.

Sensors (Basel, Switzerland)·2025
Same author

Predicting the effectiveness of chemotherapy treatment in lung cancer utilizing artificial intelligence-supported serum N-glycome analysis.

Computers in biology and medicine·2025
Same author

A general text mining method to extract echocardiography measurement results from echocardiography documents.

Artificial intelligence in medicine·2023

Related Experiment Video

Updated: May 10, 2025

Directed Evolution Method in Saccharomyces cerevisiae: Mutant Library Creation and Screening
10:50

Directed Evolution Method in Saccharomyces cerevisiae: Mutant Library Creation and Screening

Published on: April 1, 2016

10.8K

Outpatient Scheduling with Genetic Algorithm: The Power of Mutation Operators.

Veronika Gombás1, Péter Bálint Scsibrán1, Tibor Dulai1

  • 1Department of Computer Science and Systems Technology, University of Pannonia, Veszprem, Hungary.

Studies in Health Technology and Informatics
|April 24, 2025
PubMed
Summary

A specialized genetic algorithm significantly improves outpatient scheduling by using an exponential mutation operator. This approach enhances efficiency and minimizes examination completion times in complex scheduling tasks.

Keywords:
Outpatient schedulinggenetic algorithmmutation operator

More Related Videos

Optogenetic Random Mutagenesis Using Histone-miniSOG in C. elegans
04:51

Optogenetic Random Mutagenesis Using Histone-miniSOG in C. elegans

Published on: November 14, 2016

9.0K
Following the Dynamics of Structural Variants in Experimentally Evolved Populations
04:52

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Published on: February 3, 2023

898

Related Experiment Videos

Last Updated: May 10, 2025

Directed Evolution Method in Saccharomyces cerevisiae: Mutant Library Creation and Screening
10:50

Directed Evolution Method in Saccharomyces cerevisiae: Mutant Library Creation and Screening

Published on: April 1, 2016

10.8K
Optogenetic Random Mutagenesis Using Histone-miniSOG in C. elegans
04:51

Optogenetic Random Mutagenesis Using Histone-miniSOG in C. elegans

Published on: November 14, 2016

9.0K
Following the Dynamics of Structural Variants in Experimentally Evolved Populations
04:52

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Published on: February 3, 2023

898

Area of Science:

  • Operations Research
  • Computer Science
  • Healthcare Management

Background:

  • Outpatient scheduling presents significant complexity and time demands.
  • Optimization methods, including genetic algorithms, have been explored to address these challenges.

Purpose of the Study:

  • Develop a task-specific genetic algorithm for outpatient scheduling.
  • Evaluate the impact of various mutation operators on algorithm performance.
  • Minimize the earliest completion time for scheduled examinations.

Main Methods:

  • Designed and compared random and two heuristic mutation operators.
  • Assessed operator performance across four distinct scheduling scenarios.
  • Focused on optimizing examination scheduling.

Main Results:

  • The exponential mutation operator demonstrated superior performance across all scenarios.
  • Achieved optimal schedules in 100% of runs for simple tasks and 74.5% for complex tasks.
  • Outperformed random and polynomial mutation operators significantly.

Conclusions:

  • The choice of mutation operator critically affects genetic algorithm efficiency in outpatient scheduling.
  • Tailoring mutation operators to the objective function substantially enhances scheduling performance.