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Related Concept Videos

Pulse rhythm01:30

Pulse rhythm

717
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
717

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Related Experiment Video

Updated: May 10, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

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Published on: December 11, 2017

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Optimisation of Cardiac Resynchronisation Therapy with MultiPoint™ Pacing.

Antonio Curnis1, David O'Donnell2, Axel Kloppe3

  • 1Brescia Italy.

Arrhythmia & Electrophysiology Review
|April 24, 2025
PubMed
Summary
This summary is machine-generated.

Cardiac resynchronisation therapy (CRT) improves heart failure outcomes. Advanced techniques like MultiPoint pacing enhance lead placement and patient response rates, offering sustained benefits.

Keywords:
Heart failureMultiPoint pacingcardiac resynchronisation

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Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Technology

Background:

  • Cardiac resynchronisation therapy (CRT) is standard for heart failure (HF) with impaired left ventricular (LV) systolic function.
  • Optimal lead placement for CRT remains a challenge, with non-response rates around 33%.
  • Electrical mapping may improve CRT outcomes and patient selection.

Purpose of the Study:

  • To review advancements in CRT lead placement and patient selection.
  • To discuss the role of MultiPoint™ pacing in improving CRT efficacy.
  • To present findings from a symposium on optimizing CRT outcomes.

Main Methods:

  • Discussion of electrical mapping techniques for CRT lead placement.
  • Review of clinical studies on MultiPoint™ pacing with quadripolar leads.
  • Analysis of haemodynamic and clinical benefits of MultiPoint™ pacing versus conventional biventricular pacing.

Main Results:

  • MultiPoint™ pacing increases the likelihood of identifying optimal pacing sites.
  • Clinical studies show haemodynamic and clinical benefits with MultiPoint™ pacing in HF patients.
  • These benefits were sustained at 12 months post-procedure.

Conclusions:

  • Optimizing lead placement through electrical mapping and advanced pacing technologies like MultiPoint™ pacing can improve CRT response rates.
  • MultiPoint™ pacing offers sustained haemodynamic and clinical advantages over conventional biventricular pacing.
  • Technological advancements are crucial for enhancing patient outcomes in CRT for heart failure.