Concurrent Myocardial Bridging and Coronary Artery Disease: A Study of an Iranian Population
Danial Chaleshi1,2, Fahime Samadi1, Amir Ali Ghaemi3
1Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Insights
Myocardial bridging (MB) affects 4.4% of symptomatic patients in Iran, commonly in the left anterior descending artery. This study explored MB prevalence and its link to coronary artery disease (CAD).
Area of Science:
- Cardiology
- Diagnostic Imaging
- Epidemiology
Background:
- Myocardial bridging (MB) is linked to serious cardiac events like acute coronary syndrome and sudden death.
- Understanding the prevalence and manifestations of MB is crucial for patient management.
- Previous research highlights the potential complications associated with this congenital anomaly.
Purpose of the Study:
- To determine the prevalence of myocardial bridging (MB) in symptomatic coronary patients in Iran.
- To investigate the common locations and associated coronary artery disease (CAD) patterns in patients with MB.
- To analyze the clinical and radiological characteristics of patients diagnosed with MB.
Main Methods:
- A cross-sectional study involving 3750 symptomatic coronary patients undergoing angiography.
- Evaluation of angiographic reports and films by an interventional cardiologist for MB diagnosis.
- Statistical analysis using SPSS (version 20.0) with the chi-squared test to assess variable distributions.
Main Results:
- Myocardial bridging (MB) was diagnosed in 165 (4.4%) of the studied patients.
- The left anterior descending artery was the most frequent site for MB (92.1%).
- Commonly associated coronary artery disease (CAD) included mono-vessel disease (35.1%) and slow flow (25.8%).
Conclusions:
- This study offers insights into the prevalence of myocardial bridging (MB) in Iran.
- The findings highlight the association of MB with specific coronary artery disease (CAD) presentations.
- Further research is needed to understand discrepancies with previous studies and clinical implications.
Background:
Myocardial bridging (MB) has been associated with acute coronary syndrome, ischemia, arrhythmia, and even sudden death. This study investigated the prevalence of MB and its complications and manifestations.
Methods:
This cross-sectional study was conducted on symptomatic coronary patients who underwent angiography between March 2022 and March 2023 at Afshar or Shahid Sadoughi hospitals in Yazd, Iran. The angiographic reports of all patients were evaluated. Cases with MB were selected, and their angiographic films were assessed by an interventional cardiologist for diagnostic accuracy. Baseline, radiological, and clinical characteristics were also evaluated. Data were collected and analyzed using SPSS, version 20.0. The dependent variable was stratified based on independent variables using the χ2 test.
Results:
Out of 3750 symptomatic patients, 165 (4.4%) were diagnosed with MB. Among these, 111 (67.3%) were male, and the mean age was 56.87±10.06 years. A total of 152 patients had MB in the left anterior descending artery, representing the highest occurrence proportion at 92.1%. The most common types of coronary artery disease (CAD) diagnosed included mono-vessel disease and slow flow, accounting for 35.1% and 25.8%, respectively. There was no significant frequency distribution of CAD co-occurrence based on baseline and radiological features (P>0.050).
Conclusion:
This study provides valuable insights into the prevalence of MB in Iran and its co-occurrence with CAD. While some findings align with previous research, certain discrepancies warrant further investigation.
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