Comorbid Diabetes Mellitus Contributes to Residual Overactive Bladder After Transurethral Surgery for Benign...

Area of Science:

• Urology
• Andrology
• Metabolic Syndrome Research

Background:

• Overactive bladder (OAB) symptoms can persist after surgery for benign prostatic hyperplasia (BPH).
• Identifying factors predicting residual OAB is crucial for patient management and surgical outcomes.

Purpose of the Study:

• To investigate factors associated with residual overactive bladder (OAB) after transurethral surgery for benign prostatic hyperplasia (BPH).
• To identify predictive factors for persistent OAB symptoms post-surgery.

Main Methods:

• Retrospective analysis of male patients (≥50 years) who underwent transurethral surgery for BPH with OAB.
• Comparison of preoperative factors, symptom scores (IPSS, OABSS), uroflowmetry, and pressure flow studies between poor and good OAB responders post-surgery.
• Multivariate analysis to determine risk factors for residual OAB.

Main Results:

• Poor OAB responders showed a higher prevalence of metabolic syndrome, including larger waist circumference and history of diabetes treatment.
• Preoperative maximum flow rate was higher, and bladder outlet obstruction index was lower in poor responders.
• Multivariate analysis identified history of diabetes treatment and lower bladder outlet obstruction index as significant predictors of residual OAB.

Conclusions:

• History of diabetes treatment and a lower bladder outlet obstruction index are predictive factors for residual overactive bladder after BPH surgery.
• These findings can potentially improve the prediction of OAB outcomes in patients undergoing transurethral surgery for BPH.