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Published on: September 14, 2009
Factors Associated With Chronic Stent Recoil and its Impact on Revascularization: A Serial Optical Coherence
Yoichiro Sugizaki1, Yu-Wei Chen2, Takunori Tsukui2
1Clinical Trials Center, Cardiovascular Research Foundation, New York, New York, USA; Department of Cardiology, St. Francis Hospital, Roslyn, New York, USA; Division of Cardiology, Department of Medicine, Columbia University Medical Center/NewYork-Presbyterian Hospital, New York, New York, USA.
Chronic stent recoil, a significant issue in drug-eluting stent implantation, occurred in 1 in 5 lesions requiring target lesion revascularization (TLR). This finding highlights the association between chronic stent recoil and TLR, emphasizing its clinical relevance.
Area of Science:
- Cardiovascular Interventions
- Medical Device Technology
- Interventional Cardiology
Background:
- Chronic stent recoil, a phenomenon influenced by stent materials and designs, can impact long-term outcomes.
- Understanding the incidence and implications of chronic stent recoil is crucial for optimizing stent-based therapies.
Purpose of the Study:
- To investigate the incidence of chronic stent recoil using serial optical coherence tomography (OCT).
- To determine the impact of chronic stent recoil on target lesion revascularization (TLR) in patients receiving second- or newer-generation drug-eluting stents.
Main Methods:
- Serial OCT studies were performed at baseline and either at TLR or after >6 months follow-up.
- Chronic stent recoil was defined by >10% stent volume reduction or >10% cross-sectional area reduction, with or without fracture/deformation.
- Multivariable logistic regression models were used to identify predictors of chronic stent recoil and TLR.
Main Results:
- Chronic stent recoil was observed in 21.5% of lesions undergoing TLR versus 7.8% not undergoing TLR.
- Factors associated with increased risk of chronic stent recoil included larger calcium arc, greater baseline stent expansion, and higher stent eccentricity.
- Greater chronic stent recoil, increased in-stent tissue growth, and smaller baseline minimum stent area were associated with TLR.
Conclusions:
- Chronic stent recoil affects approximately 1 in 5 lesions undergoing TLR after second- or newer-generation drug-eluting stent implantation.
- Chronic stent recoil is significantly associated with target lesion revascularization, underscoring its clinical importance.
