Related Experiment Video For Adjuvant immunotherapy
Updated: May 10, 2025

Comparing Metastatic Clear Cell Renal Cell Carcinoma Model Established in Mouse Kidney and on Chicken Chorioallantoic Membrane
Published on: February 8, 2020
[First diagnosis of renal cell carcinoma via a testicular metastasis]
Leonhard Buck1, Hans Christoph von Knobloch2, Jakob Kohler2
1Klinik für Urologie, Universitätsklinikum Schleswig-Holstein - Campus Kiel, Kiel, Deutschland. Leonhard.Buck@uksh.de.
Abstract:
This case report describes a rare case of testicular metastasis from renal cell carcinoma, which led to first diagnosis of the primary. The patient presented with a progressive painless swelling of the left testicle. After initial suspicion of a testicular tumor, inguinal excision of the testis was performed, which confirmed the presence of a clear cell carcinoma. Further investigations revealed evidence of a primary carcinoma on the left-lower pole of the kidney, which was removed by partial nephrectomy. Histopathologically, clear cell renal cell carcinoma was confirmed. Treatment was supplemented by adjuvant immunotherapy with pembrolizumab. Postoperative follow-up has shown no evidence of recurrence to date.

