Relationship between cardio-ankle vascular index value and stroke in hypertension patients cardio-ankle vascular...

Area of Science:

• Vascular Medicine
• Cardiology
• Neurology

Background:

• The cardio-ankle vascular index (CAVI) is an emerging biomarker for arteriosclerosis.
• Investigating CAVI's association with stroke risk in hypertensive individuals is crucial for cardiovascular health.
• Understanding the prevalence of stroke in patients with elevated CAVI (≥9) can inform clinical practice.

Purpose of the Study:

• To examine the relationship between CAVI values and stroke incidence in patients with and without hypertension.
• To specifically assess stroke prevalence in hypertension patients with CAVI ≥9 compared to those with CAVI <9.
• To identify CAVI as an independent risk factor for stroke in hypertensive populations.

Main Methods:

• A cohort of 735 patients (293 male, 442 female) were categorized into four groups based on hypertension status and CAVI (<9 or ≥9).
• CAVI was measured using the VS-1000 apparatus.
• Statistical analysis, including multiple linear regression, was employed to determine associations.

Main Results:

• Patients with higher CAVI (≥9) exhibited significantly higher prevalence of stroke and coronary artery disease, irrespective of hypertension status.
• Hypertension patients with CAVI ≥9 showed increased stroke prevalence and higher right intima-media thickness (RIMT) compared to those with CAVI <9.
• CAVI and age were identified as independent factors associated with stroke in the overall patient group.

Conclusions:

• Elevated CAVI (≥9) is linked to a higher prevalence of stroke in hypertension patients.
• CAVI is confirmed as an independent risk factor for stroke, particularly in individuals with hypertension.
• The findings underscore the importance of CAVI in assessing cardiovascular risk in hypertensive patients.