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Updated: May 10, 2025

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
Published on: June 8, 2020
An analysis of colorectal cancer in Ghana: implications for low and middle income countries
1Department of Surgery, University of Massachusetts, 55N Lake Ave Worcester, MA, 01655, USA.
Abstract:
Colorectal cancer (CRC) is a growing public health threat in low- and middle-income countries (LMICs), challenging the traditional focus on infectious diseases. This paper examines the rising burden of CRC in LMICs, using Ghana as a case study. CRC incidence is increasing in LMICs, often presenting at younger ages and later stages, with poorer survival rates. This analysis explores CRC's epidemiological trends in Ghana, highlighting management challenges: limited resources, inadequate screening, sociocultural barriers, and social determinants of health. The paper investigates the roles of stakeholders, government agencies, and frontline providers in shaping healthcare infrastructure and addressing the need for specialized care. It examines the gap in global health initiatives regarding chronic diseases such as CRC and funding/policy prioritization challenges. Finally, it proposes policy recommendations for LMICs: robust surveillance systems, tailored screening guidelines, integrated preventive measures, improved access to screening and treatment, and collaborative efforts. Addressing CRC's complex challenges in LMICs requires a shift in global health priorities, recognizing the increasing burden of chronic diseases and ensuring equitable access to prevention, screening, and treatment.
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