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Related Experiment Video

Updated: May 8, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
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Optimizing treatment selection in venous malformations through imaging-assisted sequential therapy: A case series

Weixin Wang1, Wei Lu1, Chaonan Wang1

  • 1Department of Hemangioma and Vascular Malformation, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Journal of Vascular Surgery. Venous and Lymphatic Disorders
|April 24, 2025
PubMed
Summary

Sequential treatment combining sclerotherapy and surgery effectively manages venous malformations (VMs). Imaging guides this approach for optimal outcomes in complex vascular anomalies.

Keywords:
Magnetic resonance imagingSclerotherapySequential therapySurgeryUltrasoundVenous malformations

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Area of Science:

  • Vascular Surgery
  • Medical Imaging
  • Interventional Radiology

Background:

  • Venous malformations (VMs) are common congenital vascular anomalies requiring tailored management.
  • Lesions with interstitial components present unique therapeutic challenges.
  • Individualized treatment is crucial for effective VM management.

Purpose of the Study:

  • To evaluate a sequential treatment strategy for venous malformations.
  • To assess the combination of sclerotherapy and open surgery.
  • To investigate the role of ultrasound (US) and magnetic resonance imaging (MRI) in guiding treatment.

Main Methods:

  • Retrospective analysis of 10 patients with VMs.
  • Initial sclerotherapy followed by surgical intervention.
  • Preoperative US and MRI for treatment monitoring and surgical timing.

Main Results:

  • Sclerotherapy reduced venous components and blood supply via fibrosis.
  • Sequential surgery successfully removed interstitial components, improving cosmetic outcomes.
  • US and MRI effectively monitored treatment, with MRI crucial for complex cases.

Conclusions:

  • Sequential sclerotherapy and surgery offer effective VM management.
  • Tailored surgical planning guided by imaging is essential.
  • Larger studies are needed to validate and optimize protocols.