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Psychometric evaluation of the Hamilton Inventory to evaluate signs and symptoms in patients with Complex Regional
Maryam Farzad1, Tara Packham2, Joy MacDermid3
1Hand and Upper Limb Center, St. Joseph's Health Center, School of Physical Therapy, Department of Health and Rehabilitation Sciences, University of Western Ontario, London, Ontario, Canada; School of Occupational Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Insights
The Persian version of the Hamilton Inventory for Complex Regional Pain Syndrome (HI-CRPS) is a reliable tool for assessing CRPS symptoms and impacts. This validated instrument shows good consistency and accuracy in evaluating patients with CRPS.
Area of Science:
- Pain Management
- Clinical Psychology
- Rehabilitation Medicine
Background:
- Complex Regional Pain Syndrome (CRPS) significantly impacts patients physically and psychologically.
- Effective evaluation of CRPS requires comprehensive assessment tools.
Purpose of the Study:
- To validate the Persian version of the Hamilton Inventory for Complex Regional Pain Syndrome (HI-CRPS).
- To assess the reliability and validity of the Persian HI-CRPS in CRPS patients.
Main Methods:
- A cross-sectional clinical measurement study was conducted.
- 64 CRPS patients completed Persian versions of the HI-CRPS (patient-reported and clinician-based).
- Reliability, validity, and responsiveness were evaluated using established statistical methods.
Main Results:
- The Persian HI-CRPS showed satisfactory internal consistency (Cronbach's alpha: 0.71-0.91) and robust test-retest reliability (ICC: 0.86-0.97).
- Construct validity was confirmed through significant correlations with related measures (p < 0.01).
- Responsiveness was demonstrated with an effect size of 0.79 and SRM of 0.88 for the patient-reported version.
Conclusions:
- The Persian HI-CRPS is a valid and reliable instrument for CRPS assessment.
- The tool effectively measures CRPS symptoms, functional limitations, and psychosocial effects.
- This validated Persian version supports better clinical evaluation and management of CRPS patients.
Background:
Complex Regional Pain Syndrome (CRPS) is a debilitating condition with profound physical and psychological impacts, necessitating comprehensive assessment tools for effective evaluation.
Purpose:
This study aimed to validate the Persian version of the Hamilton Inventory for Complex Regional Pain Syndrome (HI-CRPS) and assess its reliability and validity in individuals diagnosed with CRPS.
Study Design:
A cross-sectional clinical measurement study evaluated the Persian version of HI-CRPS.
Methods:
A sample of 64 individuals diagnosed with CRPS from pain and hand surgeon clinics completed the Persian versions of the patient-reported (PR-HI-CRPS) and clinicians based (CB-HI-CRPS). Test-retest reliability was assessed after 1 week, and responsiveness was measured after 3 months. Baseline scores, ceiling effects, internal consistency (Cronbach's alpha), and construct validity (correlations with related measures) were examined. Effect sizes and standardized response means (SRM) were calculated to gauge responsiveness.
Results:
Baseline scores for PR-HI-CRPS and CB-HI-CRPS were 77.8 and 14.9, respectively. Around 18% of PR-HI-CRPS and 16% of CB-HI-CRPS respondents exhibited ceiling effects. Internal consistency for PR-HI-CRPS (Cronbach's alpha: 0.71-0.91) and CB-HI-CRPS (alpha: 0.90) was satisfactory. PR-HI-CRPS (ICC: 0.86) and CB-HI-CRPS (ICC: 0.97) showed robust test-retest reliability. Construct validity was confirmed by significant correlations between PR-HI-CRPS subscales and related measures (p < 0.01). Structural validity was confirmed by confirmatory factor analysis. PR-HI-CRPS displayed an effect size of 0.79 and a standardized response mean (SRM) of 0.88.
Conclusions:
The Persian version of the HI-CRPS demonstrated satisfactory internal consistency, test-retest reliability, construct validity, and responsiveness. It can be relied upon to assess CRPS symptoms, functional limitations, and psychosocial impacts.

