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Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

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Published on: September 30, 2020

Association between physical function and hospitalization among older patients with pre-dialysis chronic kidney

Aki Tabata¹, Hiroki Yabe², Takehide Katogi¹

¹Department of Rehabilitation, Seirei Sakura Citizen Hospital, Chiba, Japan.

Therapeutic Apheresis and Dialysis : Official Peer-Reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy

|April 24, 2025

Abstract

Introduction:

This study aimed to investigate the factors associated with hospitalization in older patients with pre-dialysis CKD, including physical function.

Methods:

This single-center, prospective cohort study included 111 patients aged ≥65 years with stage 3-5 non-hemodialyzed CKD. Physical function was assessed using the short physical performance battery (SPPB), 10-m walk test, and grip strength test. Hospitalizations and reasons for readmission were tracked from discharge to the end of the follow-up period.

Results:

Kaplan-Meier analysis showed significant associations between rehospitalization and SPPB, 10-meter walk speed, and grip strength. The cutoff values predicting rehospitalization were 11 points for SPPB, 1.1 m/s for 10-meter walk speed, and 31 kg for grip strength. Multivariate Cox regression revealed that SPPB, hemoglobin, and estimated glomerular filtration rate (eGFR) were independently associated with rehospitalization risk.

Conclusions:

SPPB may predict hospitalization in older pre-dialysis CKD patients, emphasizing the importance of screening and preventing physical function decline.

Keywords:

chronic kidney disease hospitalization older patients physical function pre‐dialysis

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