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Related Experiment Videos

[Parenteral hyperalimentation (author's transl)].

H Göschke, A Leutenegger

    Wiener Klinische Wochenschrift
    |March 4, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Intravenous hyperalimentation can cause hyperglycemia, especially during stress. Glucose is generally preferred, but glucose substitutes may help manage difficult cases in intensive care.

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    Area of Science:

    • Metabolism and Nutrition
    • Intensive Care Medicine

    Context:

    • Intravenous hyperalimentation provides complete nutrition for patients unable to eat orally.
    • Complications like hyperglycemia and sepsis can occur.
    • Stress significantly impacts glucose metabolism in intensive care patients.

    Purpose:

    • To investigate the causes and management of hyperglycemia during intravenous hyperalimentation.
    • To compare glucose tolerance with different intravenous feeding substrates.
    • To review alternative nutrition methods and side-effect prevention.

    Summary:

    • 18% of intensive care patients on hyperalimentation experienced hyperglycemia despite insulin.
    • Stress, associated with decreased insulin and increased counter-regulatory hormones, contributes to glucose intolerance.

    Related Experiment Videos

  • A mixture of glucose, fructose, and xylitol required lower insulin doses and resulted in lower plasma glucose levels compared to pure glucose infusion.

    • Impact:

    • Findings suggest glucose is generally preferred for intravenous feeding.
    • Partial replacement of glucose with substitutes or fat emulsions may be beneficial for managing refractory hyperglycemia.
    • Less invasive feeding methods like nasogastric or peripheral venous nutrition should be considered when appropriate.