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Essential Minerals for Bone Health

Essential Minerals for Bone Health

The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...

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Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.

Chun Ho Hung¹, Yui Chit Kwok¹, Jason Yip¹

¹Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China; leohung@connect.hku.hk (C.H.H.); walterk6@connect.hku.hk (Y.C.K.); u3571854@connect.hku.hk (J.Y.); jackyhhw@connect.hku.hk (H.H.W.).

Craniomaxillofacial Trauma & Reconstruction

|April 25, 2025

Summary

Bioabsorbable magnesium implants offer a safe and effective alternative for bone fixation in orthopedic surgeries, showing lower revision rates and high bone union compared to traditional materials.

Keywords:

absorbable bone surgery fixation magnesium osteosynthesis

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Biological Compatibility Profile on Biomaterials for Bone Regeneration

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Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Area of Science:

Biomaterials Science
Orthopedic Surgery
Materials Engineering

Background:

Bioabsorbable magnesium (Mg) materials are emerging as promising alternatives for bone fixation.
Traditional metallic implants like titanium (Ti) have limitations, including the need for removal.
Evaluating the clinical efficacy and safety of Mg-based implants is crucial for their wider adoption.

Purpose of the Study:

To systematically review and analyze the clinical outcomes, safety profile, and applications of bioabsorbable Mg-based materials in bone fixation surgeries.
To compare the performance of Mg implants against conventional Ti implants regarding revision rates, bone union, and infection.

Main Methods:

A systematic literature review was conducted following the PRISMA statement guidelines.
Searches were performed across electronic databases, supplemented by manual and reference list searches.
Included studies were qualitatively analyzed for patient data, biocompatibility, revision surgery rates, bone union, gas formation, and serum Mg/Ca levels.

Main Results:

Eight studies with 386 patients were included in the final analysis.
The Mg group demonstrated a significantly lower revision surgery rate (1/275) compared to the Ti group (18/111).
High bone union rates and a low infection incidence (3/275) were observed in the Mg group, with no significant impact on serum Mg and Ca levels.

Conclusions:

Bioabsorbable magnesium implants represent a safe and resorbable alternative for bone fixation in orthopedic applications.
Current applications exclude oral and maxillofacial surgeries, highlighting a need for further research.
Future investigations should focus on expanding Mg implant applications across diverse anatomical sites to maximize patient benefits.